Alyssa Wu is a PhD student in the Department of Biochemistry at Western University. She is conducting BCC-funded breast cancer research under the mentorship of Dr. Shawn Li.
- Could you share your motivation/personal connection to breast cancer research?
My motivation for breast cancer research stems from a deeply personal connection. Several years ago, a close family member was diagnosed with breast cancer, profoundly impacting my life. Witnessing their journey ignited a passion to contribute meaningfully to the fight against this disease. It is this personal experience that drives my dedication to conducting research aimed at improving outcomes and quality of life for breast cancer patients. Every breakthrough, no matter how small, represents hope for those affected by breast cancer, including my loved one. Ultimately, my goal is to make a positive impact in breast cancer research, helping to create a future where this disease no longer poses a threat.
- What specific areas of breast cancer research are you currently focusing on, and why are they important?
In my breast cancer research, I’m exploring the role of proteins called AXL and MET in driving the aggressive growth and spread of triple-negative breast cancer. Understanding how these proteins and others are influencing the behavior of triple-negative breast cancer is important, since this types of breast cancer often lacks targeted treatment options. Additionally, I’m investigating how cancer cells interact with their surrounding environment to promote tumour growth and evade therapy. By uncovering these interactions, we aim to develop more personalized and effective treatments that disrupt the supportive environment for cancer cells. Ultimately, my research strives to improve outcomes and quality of life for breast cancer patients.
- What recent breakthroughs or discoveries in Canadian breast cancer research are exciting to you?
Recent breakthroughs in Canadian breast cancer research that excite me include advancements in personalized medicine, such as identifying genetic markers that predict treatment response and outcomes for patients. Additionally, novel immunotherapy approaches that harness the body’s immune system to target breast cancer cells are promising and may offer new treatment options. Furthermore, research into the tumour microenvironment and its role in tumour progression is providing valuable insights into potential new therapeutic targets. Canadian researchers are also leading efforts to address disparities in breast cancer care and outcomes among diverse populations, which is crucial for improving equity in healthcare. Overall, these discoveries offer hope for more effective and tailored treatments that will ultimately benefit breast cancer patients in Canada and beyond.
- How do you see the future of breast cancer prevention, screening, diagnosis, treatment evolving through research?
In the future, breast cancer prevention may become more personalized, with interventions tailored to individual risk factors and genetic profiles. Screening methods are likely to become more advanced, incorporating technologies like artificial intelligence to improve accuracy and early detection rates. Diagnosis may involve non-invasive techniques and liquid biopsies, offering quicker and less invasive means of identifying breast cancer. Treatment approaches will continue to advance, with targeted therapies and immunotherapies playing increasingly prominent roles, while minimizing side effects through precision medicine. Overall, research will drive a shift towards more effective, personalized, and less invasive strategies across all stages of breast cancer management.
- What advice do you have for young individuals interested in pursuing a career in breast cancer research?
For young individuals interested in pursuing a career in breast cancer research, I would advise first gaining a strong foundation in biology, biochemistry, and related fields through education and hands-on experience. Seek out opportunities to volunteer or intern in breast cancer research labs to gain exposure to the field and understand the research process. Stay informed about the latest advancements and breakthroughs in breast cancer research by reading scientific literature and attending conferences. Network with professionals in the field to learn from their experiences and gain insights into potential career paths. Lastly, remain passionate and dedicated to making a difference in the fight against breast cancer, as persistence and commitment are key to success in this challenging but rewarding field.
